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Natural Organic Coffee Acid For Loss Weight

English name:Coffee acid
CAS No: 331-39-5
Molecular formula: C9H8O4
Molecular weight: 180.16
EINECS number: 206-361-2

 Natural Organic Coffee Acid For Loss Weight

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Product introduction

The coffee acid name is "3-(3,4-dihydroxyphenyl)-2-acrylic acid". Molecular formula C9H8O4. The molecular weight is 180.16. It is present in plants such as coffee in the form of chlorogenic acid. Yellow crystals. The temperature of 223 ~ 225 ° C. The crystal precipitated from the concentrated solution contained no crystal water, and the crystal precipitated from the dilute solution contained one molecule of crystal water. Slightly soluble in cold water, soluble in hot water, cold ethanol, ethyl acetate. Its alkaline solution is orange-red. In case of ferric chloride solution, it is dark green.

 

 

Function

1. Antibacterial and antiviral: It has a wide range of bacteriostatic effects, but can be inactivated by proteins in the body. In vitro tests showed that it had antiviral activity and had a strong inhibitory effect on vaccinia and adenovirus, followed by polio type I and parainfluenza type III viruses.

2. Anti-venom: 20 μg of rattlesnake phosphodiesterase can be completely inhibited by caffeic acid at a dose of 3 μg, which is used as an anti-venom agent.

3. Other effects: Caffeic acid can increase the central excitability of rats when taken orally or intraperitoneally; oral administration can increase the secretion of hydrochloric acid in the human stomach and slow down the pulse; it can enhance the tension of the uterus. It is antagonized by papaverine, while atropine can not affect; it can promote bile secretion in rats. It has the effects of raising white blood cells, stopping bleeding and inactivating vitamin B1. It can inhibit the formation of lipid peroxide in rat brain tissue homogenate. It has the effect of shortening the time of blood coagulation and bleeding.

4. Toxicity: The LD50 of mice was intraperitoneal injection of 1583mg/kg; rabbits were injected intravenously 14mg/kg/day for 10 consecutive days, and no pathological changes were found in heart, liver, kidney function and anatomical examination.

 

Application

Among the many active ingredients of propolis, phenethyl caffeate has been identified as one of the main active components in propolis, and many of the biological activities of propolis are related to CPAE. At the same time, it also has anti-inflammatory and anti-tumor effects, and is an important raw material and intermediate for medicine.

Caffeic acid can be safely used in cosmetics, has a wide range of antibacterial and antiviral activities, and can absorb ultraviolet rays. The low concentration has the effect of inhibiting the formation of melanin in the skin, and the amount is 0.5 to 2% in the whitening beauty product. It can be used as an auxiliary agent for oxidative hair dyes, which is beneficial to enhance the strength of color.

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